Peptide-Based Membrane Fusion Inhibitors Targeting HCoV-229E Spike Protein HR1 and HR2 Domains

Human coronavirus 229E (HCoV-229E) infection in infants, elderly people, and immunocompromised patients can cause severe disease, thus calling for the development of effective and safe therapeutics to treat it. Here we reported the design, synthesis and characterization of two peptide-based membrane...

Descripción completa

Detalles Bibliográficos
Autores principales: Xia, Shuai, Xu, Wei, Wang, Qian, Wang, Cong, Hua, Chen, Li, Weihua, Lu, Lu, Jiang, Shibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855709/
https://www.ncbi.nlm.nih.gov/pubmed/29415501
http://dx.doi.org/10.3390/ijms19020487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855709/
https://www.ncbi.nlm.nih.gov/pubmed/29415501
http://dx.doi.org/10.3390/ijms19020487

Ejemplares similares