Cargando…
Peptide-Based Membrane Fusion Inhibitors Targeting HCoV-229E Spike Protein HR1 and HR2 Domains
Human coronavirus 229E (HCoV-229E) infection in infants, elderly people, and immunocompromised patients can cause severe disease, thus calling for the development of effective and safe therapeutics to treat it. Here we reported the design, synthesis and characterization of two peptide-based membrane...
Autores principales: | Xia, Shuai, Xu, Wei, Wang, Qian, Wang, Cong, Hua, Chen, Li, Weihua, Lu, Lu, Jiang, Shibo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855709/ https://www.ncbi.nlm.nih.gov/pubmed/29415501 http://dx.doi.org/10.3390/ijms19020487 |
Ejemplares similares
-
Heparan Sulfate and Enoxaparin Interact at the Interface of the Spike Protein of HCoV-229E but Not with HCoV-OC43
por: Fuochi, Virginia, et al.
Publicado: (2023) -
Structural characterization of the HCoV-229E fusion core
por: Zhang, Wei, et al.
Publicado: (2018) -
Characterization of HCoV-229E fusion core: Implications for structure basis of coronavirus membrane fusion
por: Liu, Cheng, et al.
Publicado: (2006) -
Adaptation of the endemic coronaviruses HCoV-OC43 and HCoV-229E to the human host
por: Forni, Diego, et al.
Publicado: (2021) -
HCoV-229E Infects and Activates Monocytes
por: Desforges, Marc, et al.
Publicado: (2006)