Live Dynamics of 53BP1 Foci Following Simultaneous Induction of Clustered and Dispersed DNA Damage in U2OS Cells

Cells react differently to clustered and dispersed DNA double strand breaks (DSB). Little is known about the initial reaction to simultaneous induction of DSBs with different complexities. Here, we used live cell microscopy to analyse the behaviour of 53BP1-GFP (green fluorescence protein) foci form...

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Detalles Bibliográficos
Autores principales: Sollazzo, Alice, Brzozowska, Beata, Cheng, Lei, Lundholm, Lovisa, Scherthan, Harry, Wojcik, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855741/
https://www.ncbi.nlm.nih.gov/pubmed/29419809
http://dx.doi.org/10.3390/ijms19020519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855741/
https://www.ncbi.nlm.nih.gov/pubmed/29419809
http://dx.doi.org/10.3390/ijms19020519

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