miR-214-Dependent Increase of PHLPP2 Levels Mediates the Impairment of Insulin-Stimulated Akt Activation in Mouse Aortic Endothelial Cells Exposed to Methylglyoxal

Evidence has been provided linking microRNAs (miRNAs) and diabetic complications, by the regulation of molecular pathways, including insulin-signaling, involved in the pathophysiology of vascular dysfunction. Methylglyoxal (MGO) accumulates in diabetes and is associated with cardiovascular complicat...

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Detalles Bibliográficos
Autores principales: Nigro, Cecilia, Mirra, Paola, Prevenzano, Immacolata, Leone, Alessia, Fiory, Francesca, Longo, Michele, Cabaro, Serena, Oriente, Francesco, Beguinot, Francesco, Miele, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855744/
https://www.ncbi.nlm.nih.gov/pubmed/29425121
http://dx.doi.org/10.3390/ijms19020522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855744/
https://www.ncbi.nlm.nih.gov/pubmed/29425121
http://dx.doi.org/10.3390/ijms19020522

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