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Dexamethasone-Mediated Upregulation of Calreticulin Inhibits Primary Human Glioblastoma Dispersal Ex Vivo

Dispersal of Glioblastoma (GBM) renders localized therapy ineffective and is a major cause of recurrence. Previous studies have demonstrated that Dexamethasone (Dex), a drug currently used to treat brain tumor–related edema, can also significantly reduce dispersal of human primary GBM cells from neu...

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Detalles Bibliográficos
Autores principales: Nair, Mohan, Romero, Juan, Mahtabfar, Aria, Meleis, Ahmed M., Foty, Ramsey A., Corbett, Siobhan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855794/
https://www.ncbi.nlm.nih.gov/pubmed/29443896
http://dx.doi.org/10.3390/ijms19020572