Charged N-terminus of Influenza Fusion Peptide Facilitates Membrane Fusion

Cleavage of hemagglutinin precursor (HA0) by cellular proteases results in the formation of two subunits, HA1 and HA2. The N-terminal fragment of HA2, named a fusion peptide (HAfp), possess a charged, amine N-terminus. It has been shown that the N-terminus of HAfp stabilizes the structure of a helic...

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Detalles Bibliográficos
Autores principales: Worch, Remigiusz, Dudek, Anita, Krupa, Joanna, Szymaniec, Anna, Setny, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855800/
https://www.ncbi.nlm.nih.gov/pubmed/29443945
http://dx.doi.org/10.3390/ijms19020578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855800/
https://www.ncbi.nlm.nih.gov/pubmed/29443945
http://dx.doi.org/10.3390/ijms19020578

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