Benzothiophenone Derivatives Targeting Mutant Forms of Estrogen Receptor-α in Hormone-Resistant Breast Cancers

Estrogen receptor-α positive (ERα(+)) breast cancers represent 75% of all invasive breast cancer cases, while de novo or acquired resistance to ER-directed therapy is also on the rise. Numerous factors contribute to this phenomenon including the recently-reported ESR1 gene mutations such as Y537S, w...

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Detalles Bibliográficos
Autores principales: Singh, Kriti, Munuganti, Ravi S. N., Lallous, Nada, Dalal, Kush, Yoon, Ji Soo, Sharma, Aishwariya, Yamazaki, Takeshi, Cherkasov, Artem, Rennie, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855801/
https://www.ncbi.nlm.nih.gov/pubmed/29462880
http://dx.doi.org/10.3390/ijms19020579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855801/
https://www.ncbi.nlm.nih.gov/pubmed/29462880
http://dx.doi.org/10.3390/ijms19020579

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