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Benzothiophenone Derivatives Targeting Mutant Forms of Estrogen Receptor-α in Hormone-Resistant Breast Cancers

Estrogen receptor-α positive (ERα(+)) breast cancers represent 75% of all invasive breast cancer cases, while de novo or acquired resistance to ER-directed therapy is also on the rise. Numerous factors contribute to this phenomenon including the recently-reported ESR1 gene mutations such as Y537S, w...

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Detalles Bibliográficos
Autores principales:	Singh, Kriti, Munuganti, Ravi S. N., Lallous, Nada, Dalal, Kush, Yoon, Ji Soo, Sharma, Aishwariya, Yamazaki, Takeshi, Cherkasov, Artem, Rennie, Paul S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855801/ https://www.ncbi.nlm.nih.gov/pubmed/29462880 http://dx.doi.org/10.3390/ijms19020579

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