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Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis

The aggravation of renal interstitial fibrosis in the advanced-stage of chronic kidney disease is related to decreased matrix metalloproteinase-2 (MMP-2) activity, which is induced by hypoxia in the kidney; however, the specific mechanism remains unclear. We previously demonstrated that inhibition o...

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Detalles Bibliográficos
Autores principales:	Cheng, Zhengyuan, Liu, Lei, Wang, Zhi, Cai, Yingying, Xu, Qing, Chen, Pingsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855803/ https://www.ncbi.nlm.nih.gov/pubmed/29462885 http://dx.doi.org/10.3390/ijms19020581

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