Multifaceted Mechanisms of Cisplatin Resistance in Long-Term Treated Urothelial Carcinoma Cell Lines

Therapeutic efficacy of cisplatin-based treatment of late stage urothelial carcinoma (UC) is limited by chemoresistance. To elucidate underlying mechanisms and to develop new approaches for overcoming resistance, we generated long-term cisplatin treated (LTT) UC cell lines, characterised their cispl...

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Detalles Bibliográficos
Autores principales: Skowron, Margaretha A., Melnikova, Margarita, van Roermund, Joep G. H., Romano, Andrea, Albers, Peter, Thomale, Jürgen, Schulz, Wolfgang A., Niegisch, Günter, Hoffmann, Michèle J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855812/
https://www.ncbi.nlm.nih.gov/pubmed/29462944
http://dx.doi.org/10.3390/ijms19020590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855812/
https://www.ncbi.nlm.nih.gov/pubmed/29462944
http://dx.doi.org/10.3390/ijms19020590

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