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Luminal lncRNAs Regulation by ERα-Controlled Enhancers in a Ligand-Independent Manner in Breast Cancer Cells

Estrogen receptor-α (ERα) is a ligand-inducible protein which mediates estrogenic hormones signaling and defines the luminal BC phenotype. Recently, we demonstrated that even in absence of ligands ERα (apoERα) binds chromatin sites where it regulates transcription of several protein-coding and lncRN...

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Detalles Bibliográficos
Autores principales: Miano, Valentina, Ferrero, Giulio, Rosti, Valentina, Manitta, Eleonora, Elhasnaoui, Jamal, Basile, Giulia, De Bortoli, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855815/
https://www.ncbi.nlm.nih.gov/pubmed/29462945
http://dx.doi.org/10.3390/ijms19020593