Nanoluciferase Reporter Gene System Directed by Tandemly Repeated Pseudo-Palindromic NFAT-Response Elements Facilitates Analysis of Biological Endpoint Effects of Cellular Ca(2+) Mobilization

NFAT is a cytoplasm-localized hyper-phosphorylated transcription factor that is activated through dephosphorylation by calcineurin, a Ca(2+)/calmodulin-dependent phosphatase. A non-palindromic NFAT-response element (RE) found in the IL2 promoter region has been commonly used for a Ca(2+)-response re...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Takahara, Terunao, Achiha, Takuya, Shibata, Hideki, Maki, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855827/
https://www.ncbi.nlm.nih.gov/pubmed/29463029
http://dx.doi.org/10.3390/ijms19020605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855827/
https://www.ncbi.nlm.nih.gov/pubmed/29463029
http://dx.doi.org/10.3390/ijms19020605

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