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Presence of TERT Promoter Mutations is a Secondary Event and Associates with Elongated Telomere Length in Myxoid Liposarcomas

The occurrence of TERT promoter mutations has been well described in soft tissue sarcomas (STS). However, the biological role of these mutations as well as their impact on telomere length in STS is still unclear. We analyzed 116 patient samples diagnosed with 22 distinct histological subtypes of bon...

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Detalles Bibliográficos
Autores principales: Ventura Ferreira, Monica S., Crysandt, Martina, Braunschweig, Till, Jost, Edgar, Voss, Barbara, Bouillon, Anne-Sophie, Knuechel, Ruth, Brümmendorf, Tim H., Beier, Fabian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855830/
https://www.ncbi.nlm.nih.gov/pubmed/29463038
http://dx.doi.org/10.3390/ijms19020608