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Mathematical Modelling of Nitric Oxide/Cyclic GMP/Cyclic AMP Signalling in Platelets

Platelet activation contributes to normal haemostasis but also to pathologic conditions like stroke and cardiac infarction. Signalling by cGMP and cAMP inhibit platelet activation and are therefore attractive targets for thrombosis prevention. However, extensive cross-talk between the cGMP and cAMP...

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Detalles Bibliográficos
Autores principales: Kleppe, Rune, Jonassen, Inge, Døskeland, Stein Ove, Selheim, Frode
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855834/
https://www.ncbi.nlm.nih.gov/pubmed/29462984
http://dx.doi.org/10.3390/ijms19020612