Dissecting the functions of SMG5, SMG7, and PNRC2 in nonsense-mediated mRNA decay of human cells

The term “nonsense-mediated mRNA decay” (NMD) originally described the degradation of mRNAs with premature translation–termination codons (PTCs), but its meaning has recently been extended to be a translation-dependent post-transcriptional regulator of gene expression affecting 3%–10% of all mRNAs....

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Detalles Bibliográficos
Autores principales: Nicholson, Pamela, Gkratsou, Asimina, Josi, Christoph, Colombo, Martino, Mühlemann, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855955/
https://www.ncbi.nlm.nih.gov/pubmed/29348139
http://dx.doi.org/10.1261/rna.063719.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855955/
https://www.ncbi.nlm.nih.gov/pubmed/29348139
http://dx.doi.org/10.1261/rna.063719.117

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