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Transcriptional and chromatin changes accompanying de novo formation of transgenic piRNA clusters

Expression of transposable elements in the germline is controlled by Piwi-interacting (pi) RNAs produced by genomic loci termed piRNA clusters and associated with Rhino, a heterochromatin protein 1 (HP1) homolog. Previously, we have shown that transgenes containing a fragment of the I retrotransposo...

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Detalles Bibliográficos
Autores principales: Akulenko, Natalia, Ryazansky, Sergei, Morgunova, Valeriya, Komarov, Pavel A., Olovnikov, Ivan, Vaury, Chantal, Jensen, Silke, Kalmykova, Alla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855956/
https://www.ncbi.nlm.nih.gov/pubmed/29358235
http://dx.doi.org/10.1261/rna.062851.117