Mice with miR-146a deficiency develop severe gouty arthritis via dysregulation of TRAF 6, IRAK 1 and NALP3 inflammasome

BACKGROUND: MicroRNAs (miRNAs) serve as important regulators of inflammatory and immune responses and are implicated in several immune disorders including gouty arthritis. The expression of miR-146a is upregulated in the peripheral blood mononuclear cells of patients with inter-critical gout when co...

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Detalles Bibliográficos
Autores principales: Zhang, Quan-Bo, Qing, Yu-Feng, Yin, Cong-Cong, Zhou, Li, Liu, Xian-shuang, Mi, Qing-Sheng, Zhou, Jing-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855987/
https://www.ncbi.nlm.nih.gov/pubmed/29544526
http://dx.doi.org/10.1186/s13075-018-1546-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855987/
https://www.ncbi.nlm.nih.gov/pubmed/29544526
http://dx.doi.org/10.1186/s13075-018-1546-7

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