Predicting double-strand DNA breaks using epigenome marks or DNA at kilobase resolution

Double-strand breaks (DSBs) result from the attack of both DNA strands by multiple sources, including radiation and chemicals. DSBs can cause the abnormal chromosomal rearrangements associated with cancer. Recent techniques allow the genome-wide mapping of DSBs at high resolution, enabling the compr...

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Detalles Bibliográficos
Autores principales: Mourad, Raphaël, Ginalski, Krzysztof, Legube, Gaëlle, Cuvier, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856001/
https://www.ncbi.nlm.nih.gov/pubmed/29544533
http://dx.doi.org/10.1186/s13059-018-1411-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856001/
https://www.ncbi.nlm.nih.gov/pubmed/29544533
http://dx.doi.org/10.1186/s13059-018-1411-7

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