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Assaying sensory ciliopathies using calcium biosensor expression in zebrafish ciliated olfactory neurons

BACKGROUND: Primary cilia mediate signal transduction by acting as an organizing scaffold for receptors, signalling proteins and ion channels. Ciliated olfactory sensory neurons (OSNs) organize olfactory receptors and ion channels on cilia and generate a calcium influx as a primary signal in odouran...

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Detalles Bibliográficos
Autores principales: Bergboer, Judith G. M., Wyatt, Cameron, Austin-Tse, Christina, Yaksi, Emre, Drummond, Iain A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856005/
https://www.ncbi.nlm.nih.gov/pubmed/29568513
http://dx.doi.org/10.1186/s13630-018-0056-1