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Association of genetic variation in COMT gene with pain related to sickle cell disease in patients from the walk-PHaSST study

BACKGROUND: Vaso-occlusive pain episodes (VOEs) are the hallmark of sickle cell disease (SCD), and our current understanding of disease biology, treatment, and psychological covariates does not adequately explain the variability of pain in SCD. Functional variants in catechol-O-methyltransferase (CO...

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Detalles Bibliográficos
Autores principales: Zhang, Yingze, Belfer, Inna, Nouraie, Mehdi, Zeng, Qilu, Goel, Ruchika, Chu, Yanxia, Krasiy, Inna, Krishnamurti, Lakshmanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856032/
https://www.ncbi.nlm.nih.gov/pubmed/29559808
http://dx.doi.org/10.2147/JPR.S149958