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Association of genetic variation in COMT gene with pain related to sickle cell disease in patients from the walk-PHaSST study
BACKGROUND: Vaso-occlusive pain episodes (VOEs) are the hallmark of sickle cell disease (SCD), and our current understanding of disease biology, treatment, and psychological covariates does not adequately explain the variability of pain in SCD. Functional variants in catechol-O-methyltransferase (CO...
Autores principales: | Zhang, Yingze, Belfer, Inna, Nouraie, Mehdi, Zeng, Qilu, Goel, Ruchika, Chu, Yanxia, Krasiy, Inna, Krishnamurti, Lakshmanan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856032/ https://www.ncbi.nlm.nih.gov/pubmed/29559808 http://dx.doi.org/10.2147/JPR.S149958 |
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