Mutations in EEA1 are associated with allergic bronchopulmonary aspergillosis and affect phagocytosis of Aspergillus fumigatus by human macrophages

Allergic bronchopulmonary aspergillosis (ABPA) in asthma is a severe, life-affecting disease that potentially affects over 4.8 million people globally. In the UK, ABPA is predominantly caused by the fungus Aspergillus fumigatus. Phagocytosis is important in clearance of this fungus, and Early Endoso...

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Detalles Bibliográficos
Autores principales: Overton, Nicola L. D., Brakhage, Axel A., Thywißen, Andreas, Denning, David W., Bowyer, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856258/
https://www.ncbi.nlm.nih.gov/pubmed/29547649
http://dx.doi.org/10.1371/journal.pone.0185706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856258/
https://www.ncbi.nlm.nih.gov/pubmed/29547649
http://dx.doi.org/10.1371/journal.pone.0185706

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