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Mutations in EEA1 are associated with allergic bronchopulmonary aspergillosis and affect phagocytosis of Aspergillus fumigatus by human macrophages
Allergic bronchopulmonary aspergillosis (ABPA) in asthma is a severe, life-affecting disease that potentially affects over 4.8 million people globally. In the UK, ABPA is predominantly caused by the fungus Aspergillus fumigatus. Phagocytosis is important in clearance of this fungus, and Early Endoso...
Autores principales: | Overton, Nicola L. D., Brakhage, Axel A., Thywißen, Andreas, Denning, David W., Bowyer, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856258/ https://www.ncbi.nlm.nih.gov/pubmed/29547649 http://dx.doi.org/10.1371/journal.pone.0185706 |
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