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A fully automated image analysis method to quantify lung fibrosis in the bleomycin-induced rat model

Intratracheal administration of bleomycin induces fibrosis in the lung, which is mainly assessed by histopathological grading that is subjective. Current literature highlights the need of reproducible and quantitative pulmonary fibrosis analysis. If some quantitative studies looked at fibrosis param...

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Detalles Bibliográficos
Autores principales: Seger, Shanon, Stritt, Manuel, Vezzali, Enrico, Nayler, Oliver, Hess, Patrick, Groenen, Peter M. A., Stalder, Anna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856260/
https://www.ncbi.nlm.nih.gov/pubmed/29547661
http://dx.doi.org/10.1371/journal.pone.0193057