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Allele-specific DNA methylation of disease susceptibility genes in Japanese patients with inflammatory bowel disease

BACKGROUND: Inflammatory bowel disease (IBD) has an unknown etiology; however, accumulating evidence suggests that IBD is a multifactorial disease influenced by a combination of genetic and environmental factors. The influence of genetic variants on DNA methylation in cis and cis effects on expressi...

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Detalles Bibliográficos
Autores principales: Chiba, Hirofumi, Kakuta, Yoichi, Kinouchi, Yoshitaka, Kawai, Yosuke, Watanabe, Kazuhiro, Nagao, Munenori, Naito, Takeo, Onodera, Motoyuki, Moroi, Rintaro, Kuroha, Masatake, Kanazawa, Yoshitake, Kimura, Tomoya, Shiga, Hisashi, Endo, Katsuya, Negoro, Kenichi, Nagasaki, Masao, Unno, Michiaki, Shimosegawa, Tooru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856270/
https://www.ncbi.nlm.nih.gov/pubmed/29547621
http://dx.doi.org/10.1371/journal.pone.0194036