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Allele-specific DNA methylation of disease susceptibility genes in Japanese patients with inflammatory bowel disease
BACKGROUND: Inflammatory bowel disease (IBD) has an unknown etiology; however, accumulating evidence suggests that IBD is a multifactorial disease influenced by a combination of genetic and environmental factors. The influence of genetic variants on DNA methylation in cis and cis effects on expressi...
Autores principales: | Chiba, Hirofumi, Kakuta, Yoichi, Kinouchi, Yoshitaka, Kawai, Yosuke, Watanabe, Kazuhiro, Nagao, Munenori, Naito, Takeo, Onodera, Motoyuki, Moroi, Rintaro, Kuroha, Masatake, Kanazawa, Yoshitake, Kimura, Tomoya, Shiga, Hisashi, Endo, Katsuya, Negoro, Kenichi, Nagasaki, Masao, Unno, Michiaki, Shimosegawa, Tooru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856270/ https://www.ncbi.nlm.nih.gov/pubmed/29547621 http://dx.doi.org/10.1371/journal.pone.0194036 |
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