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Recurrent, low-frequency coding variants contributing to colorectal cancer in the Swedish population

Genome-wide association studies (GWAS) have identified dozens of common genetic variants associated with risk of colorectal cancer (CRC). However, the majority of CRC heritability remains unclear. In order to discover low-frequency, high-risk CRC susceptibility variants in Swedish population, we gen...

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Detalles Bibliográficos
Autores principales: Jiao, Xiang, Liu, Wen, Mahdessian, Hovsep, Bryant, Patrick, Ringdahl, Jenny, Timofeeva, Maria, Farrington, Susan M., Dunlop, Malcolm, Lindblom, Annika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856271/
https://www.ncbi.nlm.nih.gov/pubmed/29547645
http://dx.doi.org/10.1371/journal.pone.0193547