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The curious case of Gαs gain-of-function in neoplasia

BACKGROUND: Mutations activating the α subunit of heterotrimeric Gs protein are associated with a number of highly specific pathological molecular phenotypes. One of the best characterized is the McCune Albright syndrome. The disease presents with an increased incidence of neoplasias in specific tis...

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Detalles Bibliográficos
Autores principales: Innamorati, Giulio, Wilkie, Thomas M., Kantheti, Havish S., Valenti, Maria Teresa, Dalle Carbonare, Luca, Giacomello, Luca, Parenti, Marco, Melisi, Davide, Bassi, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856294/
https://www.ncbi.nlm.nih.gov/pubmed/29544460
http://dx.doi.org/10.1186/s12885-018-4133-z