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Global and gene-specific DNA methylation in adult type 2 diabetic individuals: a protocol for a systematic review

BACKGROUND: DNA methylation (global and gene-specific) has been reported as an epigenetic mechanism that could be involved in the pathogenesis of type 2 diabetes mellitus (T2DM). Furthermore, epigenetic therapy has been suggested as a future possibility for T2DM treatment. Epigenetic changes illustr...

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Detalles Bibliográficos
Autores principales: Mutize, Tinashe, Mkandla, Zibusiso, Nkambule, Bongani B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856358/
https://www.ncbi.nlm.nih.gov/pubmed/29544537
http://dx.doi.org/10.1186/s13643-018-0708-7