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Critical role of C-terminal residues of the Alzheimer's associated β-amyloid protein in mediating antiviral activity and modulating viral and bacterial interactions with neutrophils

Recent studies have shown that the Alzheimer’s associated β-amyloid protein (βA) can inhibit growth of bacteria, fungi and viruses. We reported that the 42 amino acid βA protein inhibits replication of seasonal and pandemic strains of H3N2 and H1N1 influenza A virus (IAV) in vitro and modulates acti...

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Detalles Bibliográficos
Autores principales: White, Mitchell R., Kandel, Ruth, Hsieh, I-Ni, De Luna, Xavier, Hartshorn, Kevan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856391/
https://www.ncbi.nlm.nih.gov/pubmed/29547627
http://dx.doi.org/10.1371/journal.pone.0194001