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Overlapping expression patterns and functions of three paralogous P5B ATPases in Caenorhabditis elegans

P5B ATPases are present in the genomes of diverse unicellular and multicellular eukaryotes, indicating that they have an ancient origin, and that they are important for cellular fitness. Inactivation of ATP13A2, one of the four human P5B ATPases, leads to early-onset Parkinson’s disease (Kufor-Rakeb...

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Detalles Bibliográficos
Autores principales: Zielich, Jeffrey, Tzima, Elena, Schröder, Eva Ayla, Jemel, Faten, Conradt, Barbara, Lambie, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856429/
https://www.ncbi.nlm.nih.gov/pubmed/29547664
http://dx.doi.org/10.1371/journal.pone.0194451