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Grip and slip of L1-CAM on adhesive substrates direct growth cone haptotaxis
Chemical cues presented on the adhesive substrate direct cell migration, a process termed haptotaxis. To migrate, cells must generate traction forces upon the substrate. However, how cells probe substrate-bound cues and generate directional forces for migration remains unclear. Here, we show that th...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856512/ https://www.ncbi.nlm.nih.gov/pubmed/29483251 http://dx.doi.org/10.1073/pnas.1711667115 |