Cargando…

Human Ska complex and Ndc80 complex interact to form a load-bearing assembly that strengthens kinetochore–microtubule attachments

Accurate segregation of chromosomes relies on the force-bearing capabilities of the kinetochore to robustly attach chromosomes to dynamic microtubule tips. The human Ska complex and Ndc80 complex are outer-kinetochore components that bind microtubules and are required to fully stabilize kinetochore–...

Descripción completa

Detalles Bibliográficos
Autores principales: Helgeson, Luke A., Zelter, Alex, Riffle, Michael, MacCoss, Michael J., Asbury, Charles L., Davis, Trisha N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856539/
https://www.ncbi.nlm.nih.gov/pubmed/29487209
http://dx.doi.org/10.1073/pnas.1718553115