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Human Ska complex and Ndc80 complex interact to form a load-bearing assembly that strengthens kinetochore–microtubule attachments
Accurate segregation of chromosomes relies on the force-bearing capabilities of the kinetochore to robustly attach chromosomes to dynamic microtubule tips. The human Ska complex and Ndc80 complex are outer-kinetochore components that bind microtubules and are required to fully stabilize kinetochore–...
Autores principales: | Helgeson, Luke A., Zelter, Alex, Riffle, Michael, MacCoss, Michael J., Asbury, Charles L., Davis, Trisha N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856539/ https://www.ncbi.nlm.nih.gov/pubmed/29487209 http://dx.doi.org/10.1073/pnas.1718553115 |
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