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The H3 Haplotype of the EPCR Gene Determines High sEPCR Levels in Critically Ill Septic Patients

INTRODUCTION: A soluble (s) form of the endothelial protein C receptor (EPCR) circulates in plasma and inhibits activated protein C (APC) activities. The clinical impact of sEPCR and its involvement in the septic process is under investigation. This study determined the frequencies of EPCR haplotype...

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Detalles Bibliográficos
Autores principales: Vassiliou, Alice G., Kotanidou, Anastasia, Mastora, Zafeiria, Tascini, Carlo, Cardinali, Gianluigi, Orfanos, Stylianos E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856733/
https://www.ncbi.nlm.nih.gov/pubmed/29549653
http://dx.doi.org/10.1007/s40121-018-0193-2