Physiological and therapeutic regulation of glucose homeostasis by upper small intestinal PepT1-mediated protein sensing

High protein feeding improves glucose homeostasis in rodents and humans with diabetes, but the mechanisms that underlie this improvement remain elusive. Here we show that acute administration of casein hydrolysate directly into the upper small intestine increases glucose tolerance and inhibits gluco...

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Detalles Bibliográficos
Autores principales: Dranse, Helen J., Waise, T. M. Zaved, Hamr, Sophie C., Bauer, Paige V., Abraham, Mona A., Rasmussen, Brittany A., Lam, Tony K. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856761/
https://www.ncbi.nlm.nih.gov/pubmed/29549253
http://dx.doi.org/10.1038/s41467-018-03490-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856761/
https://www.ncbi.nlm.nih.gov/pubmed/29549253
http://dx.doi.org/10.1038/s41467-018-03490-8

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