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FYVE domain-containing protein ZFYVE28 regulates EGFR-signaling in podocytes but is not critical for the function of filtration barrier in mice

The kidney ultrafiltration barrier is formed of endothelial cells, the glomerular basement membrane and podocytes. Podocytes have a central role in normal physiology and disease pathogenesis of the glomerulus. Signaling through epidermal growth factor receptor (EGFR) in podocytes mediates developmen...

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Detalles Bibliográficos
Autores principales: Zambrano, Sonia, Rodriguez, Patricia Q., Guo, Jing, Möller-Hackbarth, Katja, Schwarz, Angelina, Patrakka, Jaakko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856817/
https://www.ncbi.nlm.nih.gov/pubmed/29549365
http://dx.doi.org/10.1038/s41598-018-23104-z