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FYVE domain-containing protein ZFYVE28 regulates EGFR-signaling in podocytes but is not critical for the function of filtration barrier in mice
The kidney ultrafiltration barrier is formed of endothelial cells, the glomerular basement membrane and podocytes. Podocytes have a central role in normal physiology and disease pathogenesis of the glomerulus. Signaling through epidermal growth factor receptor (EGFR) in podocytes mediates developmen...
Autores principales: | Zambrano, Sonia, Rodriguez, Patricia Q., Guo, Jing, Möller-Hackbarth, Katja, Schwarz, Angelina, Patrakka, Jaakko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856817/ https://www.ncbi.nlm.nih.gov/pubmed/29549365 http://dx.doi.org/10.1038/s41598-018-23104-z |
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