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Transcytosis of TrkA leads to diversification of dendritic signaling endosomes

The development of the peripheral nervous system relies on long-distance signaling from target organs back to the soma. In sympathetic neurons, this long-distance signaling is mediated by target derived Nerve Growth Factor (NGF) interacting with its axonal receptor, TrkA. This ligand receptor comple...

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Detalles Bibliográficos
Autores principales: Barford, Kelly, Keeler, Austin, McMahon, Lloyd, McDaniel, Kathryn, Yap, Chan Choo, Deppmann, Christopher D., Winckler, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856830/
https://www.ncbi.nlm.nih.gov/pubmed/29549340
http://dx.doi.org/10.1038/s41598-018-23036-8