A Population Pharmacokinetic Model to Predict the Individual Starting Dose of Tacrolimus Following Pediatric Renal Transplantation

BACKGROUND: Multiple clinical, demographic, and genetic factors affect the pharmacokinetics of tacrolimus in children, yet in daily practice, a uniform body-weight based starting dose is used. It can take weeks to reach the target tacrolimus pre-dose concentration. OBJECTIVES: The objectives of this...

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Detalles Bibliográficos
Autores principales: Andrews, Louise M., Hesselink, Dennis A., van Gelder, Teun, Koch, Birgit C. P., Cornelissen, Elisabeth A. M., Brüggemann, Roger J. M., van Schaik, Ron H. N., de Wildt, Saskia N., Cransberg, Karlien, de Winter, Brenda C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856873/
https://www.ncbi.nlm.nih.gov/pubmed/28681225
http://dx.doi.org/10.1007/s40262-017-0567-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856873/
https://www.ncbi.nlm.nih.gov/pubmed/28681225
http://dx.doi.org/10.1007/s40262-017-0567-8

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