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Influence of cell type and cell culture media on the propagation of foot-and-mouth disease virus with regard to vaccine quality

BACKGROUND: Suspension culture of BHK cells allows large-scale virus propagation and cost-efficient vaccine production, while the shift to animal-component-free cell culture media without serum is beneficial for the quality and downstream processing of the product. Foot-and-mouth disease virus is st...

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Detalles Bibliográficos
Autores principales: Dill, Veronika, Hoffmann, Bernd, Zimmer, Aline, Beer, Martin, Eschbaumer, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857075/
https://www.ncbi.nlm.nih.gov/pubmed/29548334
http://dx.doi.org/10.1186/s12985-018-0956-0