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Influence of cell type and cell culture media on the propagation of foot-and-mouth disease virus with regard to vaccine quality
BACKGROUND: Suspension culture of BHK cells allows large-scale virus propagation and cost-efficient vaccine production, while the shift to animal-component-free cell culture media without serum is beneficial for the quality and downstream processing of the product. Foot-and-mouth disease virus is st...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857075/ https://www.ncbi.nlm.nih.gov/pubmed/29548334 http://dx.doi.org/10.1186/s12985-018-0956-0 |