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The interplay of reactive oxygen species and the epidermal growth factor receptor in tumor progression and drug resistance

BACKGROUND: The epidermal growth factor receptor (EGFR) plays important roles in cell survival, growth, differentiation, and tumorigenesis. Dysregulation of the EGFR is a common mechanism in cancer progression especially in non-small cell lung cancer (NSCLC). MAIN BODY: Suppression of the EGFR-media...

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Detalles Bibliográficos
Autores principales: Weng, Meng-Shih, Chang, Jer-Hwa, Hung, Wen-Yueh, Yang, Yi-Chieh, Chien, Ming-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857086/
https://www.ncbi.nlm.nih.gov/pubmed/29548337
http://dx.doi.org/10.1186/s13046-018-0728-0