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The interplay of reactive oxygen species and the epidermal growth factor receptor in tumor progression and drug resistance

BACKGROUND: The epidermal growth factor receptor (EGFR) plays important roles in cell survival, growth, differentiation, and tumorigenesis. Dysregulation of the EGFR is a common mechanism in cancer progression especially in non-small cell lung cancer (NSCLC). MAIN BODY: Suppression of the EGFR-media...

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Detalles Bibliográficos
Autores principales:	Weng, Meng-Shih, Chang, Jer-Hwa, Hung, Wen-Yueh, Yang, Yi-Chieh, Chien, Ming-Hsien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857086/ https://www.ncbi.nlm.nih.gov/pubmed/29548337 http://dx.doi.org/10.1186/s13046-018-0728-0

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