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Overexpression of Nitrogen Permease Regulator Like-2 (NPRL2) Enhances Sensitivity to Irinotecan (CPT-11) in Colon Cancer Cells by Activating the DNA Damage Checkpoint Pathway
BACKGROUND: Colorectal cancer (CRC) is the third most common cancer worldwide, making it is a serious threat to human health. It is imperative to develop new therapeutics to improve the CRC treatment efficiency. The aim of this study was to investigate the role of NPRL2 in improving sensitivity to C...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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International Scientific Literature, Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857147/ https://www.ncbi.nlm.nih.gov/pubmed/29519997 http://dx.doi.org/10.12659/MSM.909186 |