Bidirectional and long-lasting control of alcohol-seeking behavior by corticostriatal LTP and LTD

Addiction is proposed to arise from alterations in synaptic strength via mechanisms of long-term potentiation (LTP) and depression (LTD). However, the causality between these synaptic processes and addictive behaviors is difficult to demonstrate. Here we report that LTP/LTD induction altered operant...

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Detalles Bibliográficos
Autores principales: Ma, Tengfei, Cheng, Yifeng, Hellard, Emily Roltsch, Wang, Xuehua, Lu, Jiayi, Gao, Xinsheng, Huang, Cathy C.Y., Wei, Xiao-Yan, Ji, Jun-Yuan, Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857235/
https://www.ncbi.nlm.nih.gov/pubmed/29434375
http://dx.doi.org/10.1038/s41593-018-0081-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857235/
https://www.ncbi.nlm.nih.gov/pubmed/29434375
http://dx.doi.org/10.1038/s41593-018-0081-9

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