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Bidirectional and long-lasting control of alcohol-seeking behavior by corticostriatal LTP and LTD
Addiction is proposed to arise from alterations in synaptic strength via mechanisms of long-term potentiation (LTP) and depression (LTD). However, the causality between these synaptic processes and addictive behaviors is difficult to demonstrate. Here we report that LTP/LTD induction altered operant...
Autores principales: | Ma, Tengfei, Cheng, Yifeng, Hellard, Emily Roltsch, Wang, Xuehua, Lu, Jiayi, Gao, Xinsheng, Huang, Cathy C.Y., Wei, Xiao-Yan, Ji, Jun-Yuan, Wang, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857235/ https://www.ncbi.nlm.nih.gov/pubmed/29434375 http://dx.doi.org/10.1038/s41593-018-0081-9 |
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