Inhibition mechanisms of hemoglobin, immunoglobulin G, and whole blood in digital and real-time PCR

Blood samples are widely used for PCR-based DNA analysis in fields such as diagnosis of infectious diseases, cancer diagnostics, and forensic genetics. In this study, the mechanisms behind blood-induced PCR inhibition were evaluated by use of whole blood as well as known PCR-inhibitory molecules in...

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Detalles Bibliográficos
Autores principales: Sidstedt, Maja, Hedman, Johannes, Romsos, Erica L., Waitara, Leticia, Wadsö, Lars, Steffen, Carolyn R., Vallone, Peter M., Rådström, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Paper in Forefront
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857286/
https://www.ncbi.nlm.nih.gov/pubmed/29504082
http://dx.doi.org/10.1007/s00216-018-0931-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857286/
https://www.ncbi.nlm.nih.gov/pubmed/29504082
http://dx.doi.org/10.1007/s00216-018-0931-z

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