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Notch1 Signaling Regulates the Th17/Treg Immune Imbalance in Patients with Psoriasis Vulgaris

PURPOSE: To evaluate the regulating effect of Notch1 signaling on Th17/Treg immune imbalance in psoriasis vulgaris (PV). MATERIALS AND METHODS: Notch1, Hes-1, RORγt, Foxp3, IL-17, and IL-10 mRNA expression, as well as Th17 and Treg cell percentages in peripheral CD4(+) T cells, were detected by real...

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Detalles Bibliográficos
Autores principales: Ma, Lei, Xue, HaiBo, Gao, Tianqin, Gao, MeiLan, Zhang, YuJie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857325/
https://www.ncbi.nlm.nih.gov/pubmed/29686529
http://dx.doi.org/10.1155/2018/3069521