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Mitotic progression following DNA damage enables pattern recognition within micronuclei

Inflammatory gene expression following genotoxic cancer therapy is well documented, yet the events underlying its induction remain poorly understood. Inflammatory cytokines modify the tumor microenvironment by recruiting immune cells and are critical for both local and systemic (abscopal) tumor resp...

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Detalles Bibliográficos
Autores principales: Harding, Shane M, Benci, Joseph L, Irianto, Jerome, Discher, Dennis E, Minn, Andy J, Greenberg, Roger A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857357/
https://www.ncbi.nlm.nih.gov/pubmed/28759889
http://dx.doi.org/10.1038/nature23470